Recurrent Medulloblastoma 2 Years After Treatment, Radiologically Masquerading As An Olfactory Groove Meningioma.

Abstract

Introduction: Medulloblastomas are WHO grade 4, highly malignant, and mostly occurring in the posterior fossa. Objectives: This is a case report that details a tumor that occurred in a 12year old female in the olfactory groove region, with a prior two-year history of resection of cerebellar medulloblastoma and adjuvant therapy.  Methods: The patient was first diagnosed with a posterior fossa tumor, two years before this presentation, surgical resection was done and was followed by adjuvant radiotherapy. Subsequent three surveillance MRIs were normal. Presented with subtle symptoms of headache and loss of smell and taste, the MRI brain showed an extra-axial tumor in the olfactory groove region. Results: The patient underwent surgical resection of the tumor and the Histopathology report showed a classic medulloblastoma. Conclusions: Medulloblastomas are malignant tumors that can disseminate in the CSF, recurrences can therefore occur anywhere along the neuro-axis. Recurrent medulloblastoma should highly be considered a differential diagnosis in tumors occurring in a patient with prior history of medulloblastoma treatment.