Conus Medularis Neuroschistosomiasis in a 12-year old boy

Autor/innen

  • Makini Atuti Department of Surgery, Machakos Level 5 Hospital, Kenya https://orcid.org/0000-0001-8326-0462
  • Felix Nyang'wechi Nyatigo Department of Surgery, Machakos Level 5 Hospital, Kenya
  • Orlando Manuel Rios Mastrapa Department of Surgery, Machakos Level 5 Hospital, Kenya

Schlagworte:

neuroschistosomiasis, spinal cord, conus medularis, schistosomiasis

Abstract

Introduction: Neuroschistosomiasis, an infrequent consequence of schistosomal infection, typically presents with deteriorating motor and sensory function coupled with sphincter dysfunction. Diagnosis involves a clinical history, physical examination, cerebrospinal fluid studies, and imaging. Case report: We detail the case of a 12-year-old boy hailing from Machakos County, who manifested lower limb weakness and urine retention for two weeks. Examination unveiled diminished lower limb tone and areflexia, with a power grade of 0 in distal muscles below the knee and normal muscle bulk. Magnetic resonance imaging revealed a cauda equina region tumor. Subsequent histopathology after tumor-debulking surgery unveiled schistosomal-associated necrotizing granulomatous inflammation. Following tumor resection at T1-L1 and receipt of histopathology results, the patient underwent optimum pain management and praziquantel therapy. Clinical improvement ensued, albeit with distal paralysis. Conclusion: Our case highlights the necessity of heightened suspicion for cauda equina tumors in young patients from schistosoma-endemic regions, advocating early diagnosis and management involving praziquantel treatment.

Literaturhinweise

Gryseels, B., Polman, K., Clerinx, J., & Kestens, L. (2006). Human schistosomiasis. The Lancet, 368(9541), 1106-1118. https://pubmed.ncbi.nlm.nih.gov/16997665/

Sang, H. C., Muchiri, G., Ombok, M., Odiere, M. R., & Mwinzi, P. N. (2014). Schistosoma haematobium hotspots in south nyanza, western Kenya: Prevalence, distribution and Co-endemicity with schistosoma mansoni and soil-transmitted helminths. Parasites & Vectors, 7(1), 125. https://doi.org/10.1186/1756-3305-7-125

Kokaliaris, C., Garba, A., Matuska, M., Bronzan, R. N., Colley, D. G., Dorkenoo, A. M et al. (2022). Effect of preventive chemotherapy with praziquantel on schistosomiasis among school-aged children in sub-Saharan Africa: A spatiotemporal modelling study. The Lancet Infectious Diseases, 22(1), 136-149. https://doi.org/10.1016/s1473-3099(21)00090-6

Chadeka, E., Nagi, S., Sunahara, T., & Bahati, F. (2017). Spatial distribution and risk factors of Schistosoma haematobium and hookworm infections among schoolchildren in Kwale, Kenya. Neglected Tropical Diseases Journal, 17(1).

CDC. (1984, August 10). Acute schistosomiasis with transverse myelitis in American students returning from Kenya. Centers for Disease Control and Prevention. https://www.cdc.gov/mmwr/preview/mmwrhtml/00000385.htm

Pittella, J. E. (1997). Neuroschistosomiasis. Brain Pathology, 7(1), 649-662. https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1750-3639.1997.tb01080.x

Domingues ALC, Barbosa CS, Agt TFA, Mota AB, Franco CMR, Lopes EP, Loyo R, Gomes ECS. Spinal neuroschistosomiasis caused by Schistoma mansoni: cases reported in two brothers. BMC Infect Dis. 2020 Oct 2;20(1):724. doi: 10.1186/s12879-020-05428-2. PMID: 33008310; PMCID: PMC7530957.

Wanyoike, P., & Qureshi, M. (2004). Schistosoma mansoni of the conus medularis: Case report. East African Medical Journal, 81(5). file:///Users/User/Downloads/9173-Article%20Text-13139-1-10-20040820.pdf

Al-Abdulwahhab AH, Al-Sharydah AM, Al-Suhibani SS, Al-Jubran SA, Al-Haidey AK, Al-Hifzi AI, Al-Issawi W. Neuroschistosomiasis mimicking lower back pain: case report of a rare differential diagnosis in a pediatric patient. Patient Saf Surg. 2018 Oct 6;12:28. doi: 10.1186/s13037-018-0175-z. PMID: 30323860; PMCID: PMC6173919.

Salama, H., Shaker, A., Kasem, M., Badr, H., Mansour, M., Zaher, A., & Safwat, M. (2011). Schistosomal myeloradiculopathy due to schistosoma mansoni: Report on 17 cases from an endemic area. Annals of Indian Academy of Neurology, 14(2), 107. https://annalsofian.org/article.asp?issn=0972-2327;year=2011;volume=14;issue=2;spage=107;epage=110;aulast=Badr

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Veröffentlicht

2024-01-30

Zitationsvorschlag

1.
Atuti M, Nyang’wechi Nyatigo F, Mastrapa OMR. Conus Medularis Neuroschistosomiasis in a 12-year old boy. EAJNS [Internet]. 30. Januar 2024 [zitiert 22. Dezember 2024];3(1):22-6. Verfügbar unter: https://theeajns.org/index.php/eajns/article/view/214

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Rubrik

Case reports