Beyond Oncologic Outcome: - Utility Of Cognitive Outcome Assessent In Supratentorial Gliomas.

Authors

  • Jefferson Wanyoike Neurosurgery unit, Department of Surgery, University of Nairobi
  • Christopher Musau Neurosurgery unit, Department of Surgery, University of Nairobi
  • Vincent Wekesa Neurosurgery unit, Department of Surgery, University of Nairobi
  • Susan Karanja Neurosurgery unit, Kenyatta National Hospital

Abstract

Background: -Gliomas are among the commonest primary brain tumors. Despite significant advances in molecular diagnosis and elucidation of pathogenesis, the prognosis remains guarded. Surgical resection is limited by the lack of a clearly defined brain-tumour interface due to tumoral infiltration beyond the radiologically defined boundaries. Objective: Discuss the utility of cognitive assessment in the determination of functional outcomes. Methodology: - A literature review on outcomes in Gliomas. Results: Traditionally, the outcome following glioma surgery has been determined using oncologic parameters such as the extent of resection, progression-free survival and overall survival. These parameters are an incomplete representation of the patient's status. Functional outcome is a composite that includes; Activities of daily living, neurologic outcome, cognitive outcome, Seizure outcome, and HRQOL (Health-related quality of life). Oncofunctional balance is the bridge between the traditional and functional outcome measures. The cognitive outcome is a key determinant of functional outcome. This paper discusses the utility of the Addenbrooke Cognitive Assessment III as a simple, yet a sensitive tool for routine clinical use. The importance of pre and post-operative assessment in determining the cognitive outcome is also discussed.  Conclusion: Cognitive outcome is useful in the determination of tumour progression, response to treatment, palliative care goals and prognostication. 

Published

06-12-2022

How to Cite

1.
Wanyoike J, Musau C, Wekesa V, Karanja S. Beyond Oncologic Outcome: - Utility Of Cognitive Outcome Assessent In Supratentorial Gliomas. . EAJNS [Internet]. 2022 Dec. 6 [cited 2024 May 23];1(Supp 2):50. Available from: https://theeajns.org/index.php/eajns/article/view/81

Issue

Section

Conference Abstracts

Most read articles by the same author(s)

1 2 > >>