Mood Disorders Associated With Pituitary Adenoma: Review of Literature
Keywords:
pituitary adenoma, Mood disorders, Depression, anxiety, ACTH, Prolactinoma, apathy, TSH, neuropsychiatryAbstract
Pituitary adenomas are linked to various mood disorders, including depression, mania, and anxiety disorders. Additionally, these adenomas have been observed to present other psychiatric symptoms, such as eating disorders and suicidal ideation. A thorough literature review was conducted, utilizing diverse search engines, including PubMed, Cochrane, and Google Scholar. The search terms used included "pituitary adenomas," "mood disorders," "Hypothalamo-pituitary axis," "hypopituitarism," "acromegaly," "depression," "mania," and "psychosis." The selected publications comprised case reports and pertinent research articles. There is a high prevalence of comorbidity between pituitary adenomas and depressive and anxiety disorders. The manifestation of these symptoms can be attributed to the endocrine dysfunction associated with pituitary adenomas, as well as the physical impact and tumor growth. Furthermore, it has been noted that apathy syndrome and chronic fatigue syndrome may be misdiagnosed as depression among individuals in this specific patient demographic. The presence of mood disorders can influence the process of diagnosing and treating pituitary adenomas. Diseases of this nature can potentially affect patients' daily functioning and their ability to engage in social activities. These individuals require appropriate medical intervention to improve their prognosis.
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